Typically, no. Medications will not usually significantly change personality, but should affect your child’s symptoms. This is a common concern for parents because giving your child any medication is always a concern. Psychotropic medications (drugs used to treat mental health issues), often do not change your child’s personality but can lessen their psychiatric symptoms. For example, children who have depression or acute anxiety may get relief from these symptoms when taking certain medications. Parents should closely monitor their child when taking medications and report any concerns about side effects, changes in mood and personality to the prescribing physician.